Full-Scale C-Reactive Protein Detection Reagent (CRP) Clinical Significance
CRP overview
C-reactive protein (CRP) is an annular pentamer protein. Although the CRP concentration in the blood of normal persons is very low, CRP concentration rises rapidly under stress conditions such as infection, trauma, operation, tissue necrosis, and acute inflammation. In the absence of inflammation, hypersensitivity CRP is the thrombus of atherosclerosis. The formed mediators and markers can be used to monitor potential cardiovascular risk and assist in the diagnosis of cardiovascular disease.
CRP performance index
| Detection range | sample size | Sample type | Test time |
| 0.5~200mg/L | 5μl | Whole blood / serum / plasma | 3min |
CRP clinical significance
- Identification of infection (identification of bacterial and viral infection)
- Guide the use of antibiotics
- Evaluation of cardiovascular disease risk index for auxiliary diagnosis
Application of full-scale C-reactive protein
Routine C-reactive protein: monitoring of postoperative infections and complications; Monitoring the treatment of inflammation, monitoring the use of antibiotics, etc. Differential diagnosis of bacterial / viral infection.
High sensitivity C-reactive protein:As the most powerful predictor of cardiovascular disease, it can predict the risk index of myocardial infarction, coronary heart disease, stroke and other diseases; Differential diagnosis of neonatal infection.
Child
| Test results | Clinical application recommendations |
| ＞25 | Bacterial infections |
| 10～25 | It is suggested that CRP should be reduced to less than this level during antibiotic treatment of viral infections. If the course of the disease is short and the bacterial infection cannot be excluded, it is necessary to reexamine after a few hours |
| ＜10 | If the course of disease is more than 6-12 hours, bacterial infection or bacterial clearance can be basically ruled out |
Newborn (1～6 months)
| ＞2 | Prompt neonatal infection |
| Concentration drop | The treatment was effective and the condition improved( D4 ↓≥40% ) The antibiotic treatment was interrupted when the blood pressure dropped to normal |
Adult
| Test results | Clinical application recommendations |
| ＞10 | It is suggested that bacterial infection can be ruled out |
| 0 50～100 | It is often bacterial infection, but virus infection is not common |
| 25～50 | Indicates bacterial or viral infection |
| 10～25 | It is suggested that CRP should be reduced below this level during antibiotic treatment of viral infection. If the course of disease is short and bacterial infection cannot be ruled out, it should be reexamined several hours late |
| 3～10 | Cardiovascular disease: high risk, it is recommended to give anti-inflammatory and antithrombotic treatment at the same time |
| 1～3 | Cardiovascular disease: recommended to perform moderate risk, anti-inflammatory treatment, check again after 2 weeks and take an average as an observation standard |
| ＜1 | Cardiovascular disease: low risk |
| Treatment goals | hsCRP ＜1mg/L |
Clinical comparison of CRP
Company profile
Zhongxiu Science And Technology Co.,Ltd., is a high-tech enterprise engaged in the research and development, production and operation of in vitro diagnostic products. The in vitro diagnostic products developed by the company cover POCT series, microbial series, biochemical series and immune series reagents and supporting instruments.
The company has always adhered to the core concept of "fast and accurate, living up to life", committed to providing society with excellent products and services, and contributing to the cause of human health.
