5~200mg/L For Serum Amyloid A(SAA) Reference Value
SAA Overview
Serum amyloid A detection reagent (SAA) is an acute phase reaction protein secreted by the liver, which is present in a trace amount in the blood of healthy humans. When a viral or bacterial infection occurs, SAA begins to increase significantly at 3-6 hours, and it increases hundreds or even thousands of times in an acute state. SAA has a short half-life and can decline rapidly during the recovery period. It is more sensitive than CRP, and the two are combined detection It can better distinguish the types of infections and improve the diagnostic efficiency of virus infections.
SAA performance index
| Detection range | sample size | Sample type | Test time |
| 5~200mg/L | 5μl | Whole blood / serum / plasma | 3min
|
Clinical Significance Of SAA
| Dynamic monitoring
Prognosis evaluation
Guiding medication
| Virus infection sensitivity index | SAA is more sensitive than CRP during virus infection, and the combined detection of CRP and SAA is beneficial to the identification of early infectious diseases |
| Transplant rejection test indicators | Studies have found that SAA is one of the earliest indicators of rejection and can be used as a sensitive marker for early monitoring of patients with transplant rejection |
| Monitoring indicators of tumor invasion and metastasis | SAA is elevated to varying degrees in a variety of tumor patients, and its level is significantly related to the active stage, malignancy, invasion and metastasis of the tumor, so it can be used as one of the indicators for dynamic monitoring |
| Predictors of cardiovascular events | The increase in SAA concentration is positively correlated to predict the possibility of future cardiovascular events in healthy people, so SAA can be used as an indicator for early prediction and prognosis evaluation of cardiovascular events |
| Diagnostic indicators of AA amyloidosis | SAA is the precursor of AA, which plays a key role in the pathogenic process. The patient's serum SAA maintains a high concentration level for a long time, which can be used as an evaluation index for the treatment and prognosis of the disease |
Comparison Of CRP And SAA
| Index | CRP | SAA |
| Time of discovery | 1930 | 1976 |
| Clinical features | Increased bacterial infection 30% increase in viral infections | Virus infection is significantly increased Large increase in bacterial infections Infection cure has dropped significantly |
| Peak time | Rising period: 4-6 hours Platform period: 24-48 hours Half life: 18 hours | Rising period: 3-6 hours Platform period: 5-6 hours Half life: 50 minutes |
Application Department
Laboratory, emergency, ICU, Pediatrics / neonatology, respiratory, surgery, hematology, rheumatology and immunology, oncology, Nephrology, etc.
Clinical comparison of SAA
Company profile
Zhongxiu Science And Technology Co.,Ltd., is a high-tech enterprise engaged in the research and development, production and operation of in vitro diagnostic products. The in vitro diagnostic products developed by the company cover POCT series, microbial series, biochemical series and immune series reagents and supporting instruments.
The company has always adhered to the core concept of "fast and accurate, living up to life", committed to providing society with excellent products and services, and contributing to the cause of human health.
