Procalcitonin Detection Reagent(PCT)
PCT Overview
Procalcitonin (PCT) is a non hormonal glycoprotein discovered by assicot et al. In 1993. It is mainly produced under the stimulation of bacterial toxins and inflammatory cytokines, and does not increase in non infectious inflammation. At present, it has been used as an important indicator to identify bacteria and sepsis at home and abroad.
Clinical Significance Of PCT
- The first choice marker for sepsis diagnosis and detection
- Differential diagnosis of bacterial infection and viral infection
- Instruct the use of antibiotics
- Prognostic assessment
| PCT concentration (ng/ml) | Clinical significance | Disposal suggestions |
| <0.05 | Normal value | |
| 0.1~0.25 | Bacterial infection is unlikely | Antibiotics are not recommended |
| 0.25~0.5 | No or mild systemic inflammatory reaction, may be local inflammation or local infection | It is suggested to find out the cause of infection or other causes of PCT elevation and use antibiotics |
| 0.5~2 | Moderate systemic inflammatory reaction, possibly infection, or other conditions, such as inflammatory trauma, major surgery, cardiogenic shock | It is suggested to identify the possible infection factors. If infection is found, it is recommended to review PCT after 6-24 hours |
| 2-10 | The most likely cause is sepsis, severe sepsis or septic shock. The risk of organ dysfunction is high | It is recommended to review PCT every day. If PCT remains high (> 4D): reconsider the treatment of sepsis |
| ≧10 | Almost all of them are severe septicemia or septic shock, often accompanied by organ failure and high risk of death | It is recommended to monitor PCT every day to evaluate the therapeutic effect |
PCT performance index
| Detection range | sample size | Sample type | Test time |
| 0.1~100ng/mL | 60μl | Whole blood / serum / plasma | 15min |
Clinical comparison of PCT
Company profile
Zhongxiu Science And Technology Co.,Ltd., is a high-tech enterprise engaged in the research and development, production and operation of in vitro diagnostic products. The in vitro diagnostic products developed by the company cover POCT series, microbial series, biochemical series and immune series reagents and supporting instruments.
The company has always adhered to the core concept of "fast and accurate, living up to life", committed to providing society with excellent products and services, and contributing to the cause of human health.
