Cystatin C Detection Reagent (Immunofluorescence Chromatography) (CysC) Performance Index
CysC overview
The cysteine proteinase inhibitor (CPI) is known as cystatin C. Cycle in inhibition of C is cleared after the glomerular filtration, only is a kind of endogenous markers to reflect the actual changes in glomerular filtration rate, and in the proximal convoluted tubule reuptake, but were completely after heavy absorption metabolism decomposition, do not return the blood, therefore, its blood concentration is determined by glomerular filtration rate, and not dependent on any external factors, such as gender, age, diet, It is an ideal endogenous marker to reflect the change of glomerular filtration rate.
CysC performance index
| Detection range | sample size | Sample type | Test time |
| 0.2~8mg/L | 10μl | Whole blood / serum / plasma | 15min |
Clinical significance of CysC
- The ideal endogenous marker for GFR
- Early diagnosis and monitoring of renal diseases
- Renal function assessment in high-risk groups for AKI
Comparison of sensitivity of cystatin C and serum creatinine to assess GFR
| | Cystatin C | Cystatin C |
| creatinine | |
| GFR(mL/min/1.73m2) | >89 | 60-89 | 30-59 | 15-29 | <15 |
| CKD stage | 1 | 2 | 3 | 4 | 5 |
| | Renal impairment with normal/elevated GFR | Mild renal insufficiency | Moderate renal insufficiency | Severe renal insufficiency | Stage Renal Disease (ESRD) |
Application Department
Internal medicine, pediatrics, orthopedics, cardiology, gynecology, obstetrics and Gynecology, emergency, ICU, Nephrology,
Clinical comparison of CysC
Company profile
Zhongxiu Science And Technology Co.,Ltd., is a high-tech enterprise engaged in the research and development, production and operation of in vitro diagnostic products. The in vitro diagnostic products developed by the company cover POCT series, microbial series, biochemical series and immune series reagents and supporting instruments.
The company has always adhered to the core concept of "fast and accurate, living up to life", committed to providing society with excellent products and services, and contributing to the cause of human health.
