D-Dimer Detection Reagent(D-Dimer)(Immunofluorescence Chromatography) Clinical Significance
D-dimer Overview
D-dimer (D-dimer) is an important marker associated with acute thrombus, and its elevation reflects the phenomenon of increased coagulation and fibrinolytic activity in vivo. It is a kind of indicator that not only reflects the existence or continuous formation of thrombus in vivo, but also reflects the enhancement of fibrinolytic activity in vivo. Among the fibrin degradation products, D-dimer can reflect the thrombolytic activity after thrombus formation, which is of great importance for the diagnosis and treatment of clinical thrombotic diseases.
D-dimer Performance Index
| Detection range | sample size | Sample type | Test time |
| 0.1~10mg/L | 60μl | Whole blood / plasma | 5min |
D-dimer Clinical Significance
- Screening for disseminated intravascular coagulation (DIC)
- Screening for deep vein thrombosis (DVT)
- Screening for pulmonary embolism (PE)
- Diagnosis and evaluation of liver diseases and malignant tumors
- Diagnosis of cardiovascular diseases
- Application in surgical patients
- Monitoring and evaluation of thrombolytic drug therapy
| Acute thrombus forms in the circulatory system |
| vein | artery | Microvascular circulation |
| Deep vein thrombosis (DVT)
Pulmonary embolism (PE)
Intracranial venous thrombosis (CVT) | Acute coronary syndrome (ACS)
apoplexy | Disseminated intravascular coagulation (DIC) |
D-dimer Normal reference range
Different reagents have different ranges of normal values, generally <0.3mg/L or <0.5mg/L.
Application Department
Laboratory, cardiology, ICU, emergency department, pediatrics, operating room
D-dimer Clinical Comparison
| Outpatient with venous thromboembolism |
| Clinical preassessment |
| Low/moderately suspicious | Highly suspicious |
| D-Dimer<0.5mg/L | D-Dimer≧0.5mg/L |
| Thromboembolism was excluded | Thromboembolism is suggested and further examination is required |
| Do not need treatment | Clinical auxiliary examination |
| | No thrombosis | thrombosis |
| | Do not need treatment | treatment |
Company profile
Zhongxiu Science And Technology Co.,Ltd., is a high-tech enterprise engaged in the research and development, production and operation of in vitro diagnostic products. The in vitro diagnostic products developed by the company cover POCT series, microbial series, biochemical series and immune series reagents and supporting instruments.
The company has always adhered to the core concept of "fast and accurate, living up to life", committed to providing society with excellent products and services, and contributing to the cause of human health.
