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N-terminal atrial natriuretic peptide precursor (NT-proBNP) is a peptide hormone secreted by the heart, which is an important regulator of heart failure pathology and physiology. It is recommended by the ACC/AHA, the European Society of Cardiology (ESC), and the guidelines for the diagnosis and treatment of heart failure.
Detection range | sample size | Sample type | Test time |
80~20000pg/mL | 60μl | Whole blood / serum / plasma | 15min |
Acute heart failure | ||
Age | NT-proBNP(pg/ml) | Diagnosis of heart failure |
It doesn't matter what age | <300 | Exclusion heart failure |
< 50 years old | 300-450 | Heart failure is less likely to be diagnosed along with other clinical symptoms. |
50-75 years old | ≧450 | Increased risk of heart failure |
300-900 | Heart failure is less likely to be diagnosed along with other clinical symptoms. | |
≧900 | Increased risk of heart failure | |
>75 years old | 300-1800 | Heart failure is less likely to be diagnosed along with other clinical symptoms. |
≧1800 | Increased risk of heart failure | |
Chronic heart failure | ||
It doesn't matter what age | <400 | Rule out heart failure |
400- 2000 | The clinical manifestations, ECG, chest radiograph and echocardiography should be combined to make a multi-index differential diagnosis | |
≧2000 | Heart failure is a high risk |
Cardiology, emergency, ICU, respiratory, laboratory, surgery, neurology, obstetrics and Gynecology, oncology, etc
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